As a rule, we follow the technological advancements of corporate giants in tech health to help inform those of us individuals choosing to define for ourselves who we are and what we want to be. That means knowing the world and those tracking us, good and bad.
Incredible advancements are made every day by health companies seeking to do good in the world, no doubt. However, we need to follow and examine them to enhance our own capabilities and positioning. We are not victims, we are active agents in our lives. In this new topic within the theme of Health, we are exploring a company primed to give us the safe/effective delivery of next-gen nucleic acid therapies right into our cells and tissues that we’ve been waiting for since the dawn of the 21st century.
Last Health Post we offered a quick video from Jurassic Park showing that fantastic little DNA strand. We’ll those little bits, the nucleic acids, that make up those strands come in a variety of shapes and sizes. When we re-code these strands to treat disease, it can be difficult to get the body to take them into the cells and tissues. So Exicure came up with a fix. Its all about opportunity and a better mousetrap.
Exicure set out to maximize the uptake of a variety of therapeutics. So they went about redesigning the mode of transportation. Where linear models presented only a few options for uptake into a cell. Exicure’s SNA (Spherical Nucleic Acid) proprietary technology give multiple chances, due to the spherical structure, thereby increasing the likelihood that receptors in the body’s cells will match-up with the introduced therapy and that the cell will take in the proposed therapeutic. More importantly, because of its unique properties, SNA (Exicure’s Proprietary Tech) can enter into the tissues of a variety of organs beyond the liver (the conventional uptake organ). Now direct treatment can be applied to the Brain, Eye, Gastrointestinal Tract, Lungs and Skin.
The best part is it apparently does this without the added toxicity, or harmful side effects, of other treatments currently on the market. So sayeth the video anyway.
What we are saying is that structure makes all the difference. Nucleic acids therapies are revolutionary in and of themselves but getting them applied can be difficult. Exicure seeks to change that. After all, all the great products of the world don’t have an impact unless someone can get them effectively from origin to our homes, and into our lives.
By providing a new means of delivery they say they can achieve three primary benefits: increased uptake, more stability (stays in the body longer), and can be applied to a number of different body tissues beyond just the liver.
So that’s the Bio-med side. As for the business side of things, benefit three is not only the most important but also likely to be the most profitable as we see it. Because it can be applied to a host of cells/tissues/organs, the technology can be licensed across a wide range of companies producing different therapeutics, the technology becomes ultimately scalable. Therefore… profitable.
The licensing potential of these opportunities is just beginning. With so many different tissue systems ripe for therapy the chance for scale increases dramatically. For instance the neurological applications are just now being put into clinical trial…
Well, as they say the proof is in the pudding, and from one colloidal mixture to another, the pudding is in on Exicure.
Exicure simply delivers better uptake. With 2x the level of health transfer, and 4x longer survival than its competitor, Exicure delivers a better mousetrap, hands down. Linear oligo therapeutics make way for Exicure, and SNA.
Exicure simply delivers more bang for the buck if you will excuse the parlance. Not only does their stuff get in better, it sticks around longer. Exicure provides therapeutic endurance.
So, what does this all ultimately mean. When you add up a number of health issues that have few therapies to treat them and add Exicure as a delivery model, you increase the odds of new therapeutics to have an impact. Meaning – better, more effective treatment. This makes lives better and treatment means profit, a win-win!
And Exicure, is definitely placing itself in the right spot within the field. Their business model is robust and is apparently setup with the cash it needs into the next year (2022).
Have we oversimplified the matrix??? Perhaps, but we don’t think so. Exicure is straightforward providing the axes and shovels to the miners, or perhaps a better analogy is providing shipping and distribution to Amazon. Hard to get right, you bet ya’, but look at what Amazon spends to do just that?!?!?
In any case, next week, we’ll continue our dive and breakdown the community buzz. We’ll look to see what folks around the business news community seem to be saying about Exicure and their proprietary tech.
As always, make sure we are thinking for ourselves out there, doing our own homework, and cyberize our lives with the best in disruptive tech. We aren’t doctors or professional investors, we’re just the average guy out there in the free flow of the masses looking for understanding and wanting to share. For those fueled by health-tech make sure to explore our BCB Cyber Health Section in more detail! See you next time on BCB Cyber.
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